DIM (DIINDOLYLMETHANE) by BioResponse, 150 mg, 60 capsules
BOTH MEN & WOMEN
BioResponse DIM benefits men and women differently in many respects, but it has
some important benefits for both men and women, including fat burning and
increase in sensitivity to insulin. The benefits to men and women are described
MEN ~ BOOST TESTOSTERONE AND BLOCK ESTROGEN
Are you looking for a
non-prescription, effective anti-estrogen supplement that raises your levels
BioResponse DIM is an
outstanding, patented version of diindolylmethane. DIM 150 is safe for men and
has no side-effects, as long as it is taken as recommended. Men should take one
150mg capsules per day. If you are exercising or into sports, you may want to
increase that to the full dosage of two capsules (300mg) per day.
Testosterone naturally converts
to estrogen, then breaks down into "bad"and "good" estrogen
metabolites. The good to bad ratio of estrogen metabolites is increasesd by
DIM, resulting in the lowering of the bad metabolite. Results differ for men
than for women.
DIM blocks the estrogen
receptors activity, thereby raising the ratio of testosterone to estrogen. The
higher testosterone ratio means a higher sex drive, better moods, increased
muscle building and bone-strengthening resulting from workouts, and reduced
chance of an enlarged prostate!
WOMEN ~ IMPROVE ESTROGEN METABOLISM AND STABILIZE ESTROGEN
Are you looking for a
non-prescription, effective supplement to stabilize your hormonal levels as you
BioResponse DIM is an
outstanding, patented version of diindolylmethane. DIM 150 is safe for women
and has no side-effects, as long as it is taken as recommended. Women should
use a lower dosage of one half to one capsule (75-150 mg) per day.
Post-menopausal women who
take replacement hormones can improve their estrogen metabolism with DIM. Other
benefits to women include reduced weight gain, uterine, cervical and breast
health, and reduced chances of cancer.
Induction of apoptosis in human
prostate cancer cell line, PC3, by 3,3'-diindolylmethane through the
mitochondrial pathway Epidemiological studies have shown a strong correlation
between consumption of cruciferous vegetables and a lower risk of prostate
cancer. These vegetables contain glucosinolates, which during metabolism give
rise to several breakdown products, mainly indole-3-carbinol (I3C), which may
be condensed to polymeric products, especially
3,3'-diindolylmethane (DIM). It was previously shown that these indole
derivatives have significant inhibitory effects in several human cancer cell
lines, which are exerted through induction of apoptosis. We have previously
reported that I3C and DIM induce apoptosis in prostate cancer cell line.
Serving size: 2
CapsulesServings per Container: 30
Amount per Serving
BioResponse DIM (A patented diindolylmethane complex), starch,
diindolylmethane, vitamin E (as d-alpha tocopheryl succinate), soy
phosphatidyl choline, silica.
*Daily value(DV) not
Other ingredients: defatted rice bran, tocophersolan, gelatin, dicalcium
phosphate, silicon dioxide.
Free of yeast, milk, artificial
coloring or preservatives.
All About DIM by Michael A. Zeligs, M.D., and A. Scott Connelly, M.D.
This book answers critical questions
concerning both men and women regarding the balance of testosterone and
estrogen. Its importance for women lies in proper metabolism of estradiol. Its
importance for men is maintaining adequate free testosterone while assuring
proper metabolism of excess estrogen.
Read excerpts of this book about DIM below
Q: What exactly is Diindolylmethane
Diindolylmethane (DIM) is
a plant indolea, a plant compound with health-promoting properties. DIM and
other plant indoles are found in all cruciferous vegetables. Cruciferous
vegetables include cabbage, broccoli, Brussels sprouts and cauliflower. Supplementing
with DIM increases the chances for estrogen to be broken down into a higher
ratio of beneficial or good, to bad or undesirable estrogen metabolites. Taken
along with a program of regular exercise, DIM contributes to good physical
conditioning and a better metabolism in the most natural way possible by regulating
hormonal balance. DIM produces more good estrogen metabolites, which compete
with testosterone for protein binding, helping to maintain a slightly higher
free (and more active) testosterone level.
Q: How does Diindolylmethane DIM benefit testosterone activity?
Testosterone is also identified as
an anabolic hormone due to its ability to promote protein synthesis. Active
protein synthesis produces bigger muscles and stronger bones, especially in
response to exercise. This process also increases metabolic rate and consumes
fat, resulting in a leaner physique… The good estrogen metabolites along with
increased free testosterone promoted by DIM increase fat
mobilization and a fat-burning metabolism.
Diindolylmethane DIM for WomenAchieving Optimal Estrogen Metabolism
endometriosis, and uterine cervical dysplasia have been shown to improve with
DIM supplementation. . . . The use of both DIM and progesterone is recommended
for women in their forties or above who have evidence of progesterone
deficiency, such as irregular menstrual periods. DIM can help support natural
Q: Can Diindolylmethane DIM supplementation make hormonal replacement
therapy (HRT) safer?
The proven scientific benefits of DIM make it a logical choice as a dietary supplement
for use with HRT.
Q: Is testosterone really important
in womens health?
While the exact contribution of
testosterone to mood and sexual health has been more difficult to define in
women who have intact ovaries, it has been shown that testosterone supports
physiologic responses in sexual arousal. In studies of mood and depression,
testosterone alone or with estrogen was most effective in reducing depression.
Q: How does Diindolylmethane DIM unlock testosterone?
Diindolylmethane DIM promotes a consistent rise in the levels of good
estrogen metabolites. . . . Even a small increase in the concentration of good
estrogen metabolites results in higher levels of free testosterone. Even tiny
increases in amounts of free testosterone are capable of influencing mood and
behavior since the brain is home to a multitude of hormone receptors that can
be influenced by testosterone.
Q: Does Diindolylmethane DIM make DHEA a safer supplement?
DIMs action ensures that
the estrogen produced from DHEA is metabolized into good estrogen metabolites.
Diindolylmethane DIM for
helps to eliminate active estrogen from the male body by promoting its
conversion into the good estrogen metabolites. These metabolites then free up
testosterone by bumping it off the testosterone-binding proteins.
Q: Why is optimum hormone balance so
important for men?
Optimum hormone balance for men is
defined by strong testosterone activity and the lowest possible level of
Q: What role does supplemental
Diindolylmethane DIM play in an
aging-intervention plan for men?
Supplemental Diindolylmethane DIM reduces the effects of unmetabolized estrogen and
promotes testosterone action. It does this by maximizing the
testosterone-to-estrogen ratio in the body, thus increasing the activity of
testosterone. . . . Diindolylmethane DIM can improve mood, fight depression,
and support memory. . . . Diindolylmethane DIM also can be used to help address
many of the unwanted side effects of estrogen in menparticularly those that
occur with the age-related accumulation of estrogen. . . . Diindolylmethane DIM
can now be used to reduce the risk of prostate enlargement and promote a
healthy prostate. Optimum testosterone-to-estrogen hoemonal balance achieved
with the use of Diindolylmethane DIM can help to preserve a youthful urinary
tract and prevent age-related prostate growth.
Q: Can Diindolylmethane DIM be used with saw palmetto and other dietary
support for a healthy prostate?
Since DIM is specific in
its action to promote a more beneficial metabolism of estrogen, it reduces the
contribution of unmetabolized estrogen to age-related prostate gland
Getting Strong and Lean
with Diindolylmethane DIM
Q: Why is DIM
in demand by elite male athletes?
Diindolylmethane DIM supplementation
is the key to eliminating unwanted estrogen in men. For athletes, this means
increasing the metabolism of estrogen that is naturally present as well as any estrogen
that arises from the use of testosterone prohormone supplements. . . .With DIM use, you should see rapid muscle-building
results from your training as well as more efficient reduction in body fat.
Q: What is the best way to combine
DIM with a plan to build muscle?
Diindolylmethane DIM promotes an upward shift in the bodys critical
balance between testosterone and estrogen levels. . . . In scientific studies,
high testosterone-to-estrogen ratios have been linked to lean body mass, a
fat-burning metabolism, and low abdominal obesity.
Q: Can Diindolylmethane DIM alone benefit
strength training without the additional use of testosterone prohormones?
provides benefits to male and female athletes, since its estrogen-clearing
action occurs whether or not there is increased estrogen production as seen
with prohormone use. . . . DIM, by helping to convert estrogen to good estrogen
metabolites, protects stressed muscle cells and allows more efficient repair and
Q: How does better estrogen
metabolism results in improved fat metabolism?
reduces the levels of estradiol, or active estrogen, by promoting its
conversion into good estrogen metabolites. These good estrogen metabolites are
fat burners. . . . When Diindolylmethane DIM is used, a second important
fat-burning shift in metabolism also occursan increase in free testosterone
and, consequently, an increase in the testosterone-to-estrogen ratio.
Q: Can Diindolylmethane DIM supplements help me
lose weight without a strict diet and regular exercise?
Diindolylmethane DIM is
not a magic bullet that cancels out dietary and lifestyle indiscretion. The key
to fat loss with DIM is carbohydrate restriction and an emphasis on aerobic
exercise. When using Diindolylmethane DIM to assist fat loss, the preferred
diet limits carbohydrate intake to loww-glycemic foods, including broccoli,
celery, green beans, zucchini, and salad greens. These produce the smallest
increase in blood sugar levels. . . . Along with Diindolylmethane DIM
supplements, an exercise routine that includes long aerobic workouts will put
you solidly in a fat-burning mode and step up your metabolic rate. With
Diindolylmethane DIM, you will increase the release of stored fatty acids and
speec up your fat loss. . . The goal of fat loss with Diindolylmethane DIM is to
preserve muscle mass while reducing body fat with a healthy but
Q: Are Diindolylmethane DIM supplements safe?
The earlier research on
these phytochemicals as a cancer preventive in animals used huge amounts of
Diindolylmethane DIM for many months. Despite the continuous use of these
phytochemicals in multiple generations of animals, no safety problems were