DIM (DIINDOLYLMETHANE) by BioResponse, 150 mg, 60 capsules
BOTH MEN & WOMEN
BioResponse DIM benefits men and women differently in many respects, but it has some important benefits for both men and women, including fat burning and increase in sensitivity to insulin. The benefits to men and women are described below.
MEN ~ BOOST TESTOSTERONE AND BLOCK ESTROGEN
Are you looking for a non-prescription, effective anti-estrogen supplement that raises your levels free testosterone?
BioResponse DIM is an outstanding, patented version of diindolylmethane. DIM 150 is safe for men and has no side-effects, as long as it is taken as recommended. Men should take one 150mg capsules per day. If you are exercising or into sports, you may want to increase that to the full dosage of two capsules (300mg) per day.
Testosterone naturally converts to estrogen, then breaks down into "bad"and "good" estrogen metabolites. The good to bad ratio of estrogen metabolites is increasesd by DIM, resulting in the lowering of the bad metabolite. Results differ for men than for women.
DIM blocks the estrogen receptors activity, thereby raising the ratio of testosterone to estrogen. The higher testosterone ratio means a higher sex drive, better moods, increased muscle building and bone-strengthening resulting from workouts, and reduced chance of an enlarged prostate!
WOMEN ~ IMPROVE ESTROGEN METABOLISM AND STABILIZE ESTROGEN LEVELS
Are you looking for a non-prescription, effective supplement to stabilize your hormonal levels as you enter menopause?
BioResponse DIM is an outstanding, patented version of diindolylmethane. DIM 150 is safe for women and has no side-effects, as long as it is taken as recommended. Women should use a lower dosage of one half to one capsule (75-150 mg) per day.
Post-menopausal women who take replacement hormones can improve their estrogen metabolism with DIM. Other benefits to women include reduced weight gain, uterine, cervical and breast health, and reduced chances of cancer.
Induction of apoptosis in human prostate cancer cell line, PC3, by 3,3'-diindolylmethane through the mitochondrial pathway Epidemiological studies have shown a strong correlation between consumption of cruciferous vegetables and a lower risk of prostate cancer. These vegetables contain glucosinolates, which during metabolism give rise to several breakdown products, mainly indole-3-carbinol (I3C), which may be condensed to polymeric products, especially 3,3'-diindolylmethane (DIM). It was previously shown that these indole derivatives have significant inhibitory effects in several human cancer cell lines, which are exerted through induction of apoptosis. We have previously reported that I3C and DIM induce apoptosis in prostate cancer cell line.
Serving size: 2
CapsulesServings per Container: 30
Amount per Serving
BioResponse DIM (A patented diindolylmethane complex), starch, diindolylmethane, vitamin E (as d-alpha tocopheryl succinate), soy phosphatidyl choline, silica.
*Daily value(DV) not established
Other ingredients: defatted rice bran, tocophersolan, gelatin, dicalcium phosphate, silicon dioxide.
Free of yeast, milk, artificial coloring or preservatives.
All About DIM by Michael A. Zeligs, M.D., and A. Scott Connelly, M.D.
This book answers critical questions concerning both men and women regarding the balance of testosterone and estrogen. Its importance for women lies in proper metabolism of estradiol. Its importance for men is maintaining adequate free testosterone while assuring proper metabolism of excess estrogen.
Read excerpts of this book about DIM below
Q: What exactly is Diindolylmethane (DIM)?
Diindolylmethane (DIM) is a plant indolea, a plant compound with health-promoting properties. DIM and other plant indoles are found in all cruciferous vegetables. Cruciferous vegetables include cabbage, broccoli, Brussels sprouts and cauliflower. Supplementing with DIM increases the chances for estrogen to be broken down into a higher ratio of beneficial or good, to bad or undesirable estrogen metabolites. Taken along with a program of regular exercise, DIM contributes to good physical conditioning and a better metabolism in the most natural way possible by regulating hormonal balance. DIM produces more good estrogen metabolites, which compete with testosterone for protein binding, helping to maintain a slightly higher free (and more active) testosterone level.
Q: How does Diindolylmethane DIM benefit testosterone activity?
Testosterone is also identified as an anabolic hormone due to its ability to promote protein synthesis. Active protein synthesis produces bigger muscles and stronger bones, especially in response to exercise. This process also increases metabolic rate and consumes fat, resulting in a leaner physique… The good estrogen metabolites along with increased free testosterone promoted by DIM increase fat mobilization and a fat-burning metabolism.
Diindolylmethane DIM for WomenAchieving Optimal Estrogen Metabolism
Breast tenderness, endometriosis, and uterine cervical dysplasia have been shown to improve with DIM supplementation. . . . The use of both DIM and progesterone is recommended for women in their forties or above who have evidence of progesterone deficiency, such as irregular menstrual periods. DIM can help support natural progesterone production.
Q: Can Diindolylmethane DIM supplementation make hormonal replacement therapy (HRT) safer?
The proven scientific benefits of DIM make it a logical choice as a dietary supplement for use with HRT.
Q: Is testosterone really important in womens health?
While the exact contribution of testosterone to mood and sexual health has been more difficult to define in women who have intact ovaries, it has been shown that testosterone supports physiologic responses in sexual arousal. In studies of mood and depression, testosterone alone or with estrogen was most effective in reducing depression.
Q: How does Diindolylmethane DIM unlock testosterone?
Diindolylmethane DIM promotes a consistent rise in the levels of good estrogen metabolites. . . . Even a small increase in the concentration of good estrogen metabolites results in higher levels of free testosterone. Even tiny increases in amounts of free testosterone are capable of influencing mood and behavior since the brain is home to a multitude of hormone receptors that can be influenced by testosterone.
Q: Does Diindolylmethane DIM make DHEA a safer supplement?
DIMs action ensures that the estrogen produced from DHEA is metabolized into good estrogen metabolites.
Diindolylmethane DIM for MenActivating Testosterone
Diindolylmethane DIM helps to eliminate active estrogen from the male body by promoting its conversion into the good estrogen metabolites. These metabolites then free up testosterone by bumping it off the testosterone-binding proteins.
Q: Why is optimum hormone balance so important for men?
Optimum hormone balance for men is defined by strong testosterone activity and the lowest possible level of unmetabolized estrogen.
Q: What role does supplemental Diindolylmethane DIM play in an aging-intervention plan for men?
Supplemental Diindolylmethane DIM reduces the effects of unmetabolized estrogen and promotes testosterone action. It does this by maximizing the testosterone-to-estrogen ratio in the body, thus increasing the activity of testosterone. . . . Diindolylmethane DIM can improve mood, fight depression, and support memory. . . . Diindolylmethane DIM also can be used to help address many of the unwanted side effects of estrogen in menparticularly those that occur with the age-related accumulation of estrogen. . . . Diindolylmethane DIM can now be used to reduce the risk of prostate enlargement and promote a healthy prostate. Optimum testosterone-to-estrogen hoemonal balance achieved with the use of Diindolylmethane DIM can help to preserve a youthful urinary tract and prevent age-related prostate growth.
Q: Can Diindolylmethane DIM be used with saw palmetto and other dietary support for a healthy prostate?
Since DIM is specific in its action to promote a more beneficial metabolism of estrogen, it reduces the contribution of unmetabolized estrogen to age-related prostate gland enlargement.
Getting Strong and Lean with Diindolylmethane DIM
Q: Why is DIM in demand by elite male athletes?
Diindolylmethane DIM supplementation is the key to eliminating unwanted estrogen in men. For athletes, this means increasing the metabolism of estrogen that is naturally present as well as any estrogen that arises from the use of testosterone prohormone supplements. . . .With DIM use, you should see rapid muscle-building results from your training as well as more efficient reduction in body fat.
Q: What is the best way to combine supplemental Diindolylmethane DIM with a plan to build muscle?
Diindolylmethane DIM promotes an upward shift in the bodys critical balance between testosterone and estrogen levels. . . . In scientific studies, high testosterone-to-estrogen ratios have been linked to lean body mass, a fat-burning metabolism, and low abdominal obesity.
Q: Can DiindolylmethaneDIM alone benefit strength training without the additional use of testosterone prohormones?
Diindolylmethane DIM provides benefits to male and female athletes, since its estrogen-clearing action occurs whether or not there is increased estrogen production as seen with prohormone use. . . . DIM, by helping to convert estrogen to good estrogen metabolites, protects stressed muscle cells and allows more efficient repair and growth.
Q: How does better estrogen metabolism results in improved fat metabolism?
Diindolylmethane DIM reduces the levels of estradiol, or active estrogen, by promoting its conversion into good estrogen metabolites. These good estrogen metabolites are fat burners. . . . When Diindolylmethane DIM is used, a second important fat-burning shift in metabolism also occursan increase in free testosterone and, consequently, an increase in the testosterone-to-estrogen ratio.
Q: Can DiindolylmethaneDIM supplements help me lose weight without a strict diet and regular exercise?
Diindolylmethane DIM is not a magic bullet that cancels out dietary and lifestyle indiscretion. The key to fat loss with DIM is carbohydrate restriction and an emphasis on aerobic exercise. When using Diindolylmethane DIM to assist fat loss, the preferred diet limits carbohydrate intake to loww-glycemic foods, including broccoli, celery, green beans, zucchini, and salad greens. These produce the smallest increase in blood sugar levels. . . . Along with Diindolylmethane DIM supplements, an exercise routine that includes long aerobic workouts will put you solidly in a fat-burning mode and step up your metabolic rate. With Diindolylmethane DIM, you will increase the release of stored fatty acids and speec up your fat loss. . . The goal of fat loss with Diindolylmethane DIM is to preserve muscle mass while reducing body fat with a healthy but carbohydrate-restricted diet.
Q: Are Diindolylmethane DIM supplements safe?
The earlier research on these phytochemicals as a cancer preventive in animals used huge amounts of Diindolylmethane DIM for many months. Despite the continuous use of these phytochemicals in multiple generations of animals, no safety problems were observed.